Development of Boomerang-Type Intramolecular Cascade Reactions and Application to Natural Product Synthesis

Methods for Asymmetric Olefination Reactions; Development and Application to Natural Product Synthesis

Akademisk avhandling som med tillstånd av Kungl Tekniska Högskolan i Stockholm framlägges till offentlig granskning för avläggande av teknologie doktorsexamen i kemi med inrikting mot organisk kemi, onsdagen den 20 september, kl 10.00 i sal F3, KTH Lindstedsvägen 26, Stockholm. Avhandlingen försvaras på engelska. Opponent är Professor Viresh H. Rawal, University of Chicago, IL, USA. Methods for...

Cascade polycyclisations in natural product synthesis.

The efficient, stereocontrolled construction of polycyclic ring systems has long presented a formidable challenge to synthetic chemists. Cascade reactions offer a 'quick fix'--building multiple rings in a single step--and often dramatically shorten a synthetic route. In this Emerging Area article, a selection of the most recent and impressive examples of applications of this tactic to natural p...

The asymmetric intramolecular Heck reaction in natural product total synthesis.

construction and validation of translation metacognitive strategy questionnaire and its application to translation quality

like any other learning activity, translation is a problem solving activity which involves executing parallel cognitive processes. the ability to think about these higher processes, plan, organize, monitor and evaluate the most influential executive cognitive processes is what flavell (1975) called “metacognition” which encompasses raising awareness of mental processes as well as using effectiv...

Natural product-inspired cascade synthesis yields modulators of centrosome integrity.

In biology-oriented synthesis, the scaffolds of biologically relevant compound classes inspire the synthesis of focused compound collections enriched in bioactivity. This criterion is, in particular, met by the scaffolds of natural products selected in evolution. The synthesis of natural product-inspired compound collections calls for efficient reaction sequences that preferably combine multipl...